Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2'-Fucosyllactose and 3-Fucosyllactose

• Main Authors: Marit Zuurveld (Author), Pien C.J. Kiliaan (Author), Sophie E.L. van Grinsven (Author), Gert Folkerts (Author), Johan Garssen (Author), Belinda van't Land (Author), Linette E.M. Willemsen (Author)
• Format: Book
• Published: Karger Publishers, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Allergic sensitization starts with epithelial cell activation driving dendritic cells (DCs) to instruct T helper 2 (Th2) cell polarization. Food allergens trigger intestinal epithelial cell (IEC) activation. Human milk oligosaccharides may temper the allergic phenotype by shaping mucosal immune resp...