Study of the Effect of Polymorphic Markers of the NAT2 Gene on the Risk of Adverse Drug Reactions in Patients with Pulmonary Tuberculosis Who Received Isoniazid and Rifampicin

• Main Authors: A. A. Kachanova (Author), Yu. A. Pimenova (Author), G. N. Shuev (Author), K. A. Akmalova (Author), Zh. A. Sozaeva (Author), N. M. Krasnova (Author), E. A. Grishina (Author), D. A. Sychev (Author)
• Format: Book
• Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products», 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tuberculosis remains one of the most dangerous and widespread infectious diseases. More than 20 medicinal products are currently available for the treatment of tuberculosis. One of the most serious adverse drug reactions (ADRs) associated with anti-tuberculosis medicines is hepatotoxicity.The aim of...