Pharmacological Evaluation of a Novel Cannabinoid 2 (CB2) Ligand, PF-03550096, In Vitro and In Vivo by Using a Rat Model of Visceral Hypersensitivity

• Asıl Yazarlar: Akira Kikuchi (Yazar), Katsuyo Ohashi (Yazar), Yutaka Sugie (Yazar), Hiromi Sugimoto (Yazar), Hirofumi Omura (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2008-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Previous studies have shown that cannabinoid 2 (CB2)-receptor agonists might have analgesic effects on visceral hypersensitivity. To extend these results, we have determined the pharmacological characteristics of a newly designed CB2ligand, N-[(1S )-1-(aminocarbonyl)-2,2-dimethylpropyl]-3-(3-hydroxy...