Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation

• المؤلفون الرئيسيون: Jiayi Huang (مؤلف), Shiqi Hong (مؤلف), Lucas Yuan Hao Goh (مؤلف), Hailong Zhang (مؤلف), Tao Peng (مؤلف), Keat Theng Chow (مؤلف), Rajeev Gokhale (مؤلف), Vinod Tuliani (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2024-04-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities. KLEPTOSE^® HPβCD (hydroxypropyl beta-cyclodextrin) has funct...