Investigation on the Combined Effect of Hydroxypropyl Beta-Cyclodextrin (HPβCD) and Polysorbate in Monoclonal Antibody Formulation

• Үндсэн зохиолчид: Jiayi Huang (Зохиогч), Shiqi Hong (Зохиогч), Lucas Yuan Hao Goh (Зохиогч), Hailong Zhang (Зохиогч), Tao Peng (Зохиогч), Keat Theng Chow (Зохиогч), Rajeev Gokhale (Зохиогч), Vinod Tuliani (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2024-04-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Monoclonal antibodies require careful formulation due to their inherent stability limitations. Polysorbates are commonly used to stabilize mAbs, but they are prone to degradation, which results in unwanted impurities. KLEPTOSE^® HPβCD (hydroxypropyl beta-cyclodextrin) has funct...