Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis

• Главные авторы: Abdulbasit Amin (Автор), Marina Badenes (Автор), Johanna Tüshaus (Автор), Érika de Carvalho (Автор), Emma Burbridge (Автор), Pedro Faísca (Автор), Květa Trávníčková (Автор), André Barros (Автор), Stefania Carobbio (Автор), Pedro M. Domingos (Автор), Antonio Vidal-Puig (Автор), Luís F. Moita (Автор), Sarah Maguire (Автор), Kvido Stříšovský (Автор), Francisco J. Ortega (Автор), José Manuel Fernández-Real (Автор), Stefan F. Lichtenthaler (Автор), Colin Adrain (Автор)
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• Опубликовано: Elsevier, 2023-07-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Objective: The metalloprotease ADAM17 (also called TACE) plays fundamental roles in homeostasis by shedding key signaling molecules from the cell surface. Although its importance for the immune system and epithelial tissues is well-documented, little is known about the role of ADAM17 in metabolic ho...