Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.

• Main Authors: Joseph D Turner (Author), Nicholas Tendongfor (Author), Mathias Esum (Author), Kelly L Johnston (Author), R Stuart Langley (Author), Louise Ford (Author), Brian Faragher (Author), Sabine Specht (Author), Sabine Mand (Author), Achim Hoerauf (Author), Peter Enyong (Author), Samuel Wanji (Author), Mark J Taylor (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The risk of severe adverse events following treatment of onchocerciasis with ivermectin in areas co-endemic with loiasis currently compromises the development of control programmes and the treatment of co-infected individuals. We therefore assessed whether doxycycline treatment could be used without...