Induced pluripotent stem cell-derived human macrophages as an infection model for Leishmania donovani.

• Main Authors: Lore Baert (Author), Serena Rudy (Author), Mélanie Pellisson (Author), Thierry Doll (Author), Romina Rocchetti (Author), Marcel Kaiser (Author), Pascal Mäser (Author), Matthias Müller (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The parasite Leishmania donovani is one of the species causing visceral leishmaniasis in humans, a deadly infection claiming up to 40,000 lives each year. The current drugs for leishmaniasis treatment have severe drawbacks and there is an urgent need to find new anti-leishmanial compounds. However,...