Increased circulating follicular regulatory T cells in Hashimoto's thyroiditis

• Main Authors: Jiwei Zhao (Author), Yanxia Chen (Author), Zhenyao Xu (Author), Wei Yang (Author), Zhongliang Zhu (Author), Yingxiang Song (Author), Jinlin Liu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Follicular T helper (Tfh) cells are involved in the pathogenesis of Hashimoto's thyroiditis (HT), while follicular T regulatory (Tfr) cells inhibit Tfh cells, which mediate B cell responses. However, the role of Tfr cells in HT remains unclear. Methods: Forty-six healthy controls (HC...