Hemostatic dysfunction is increased in patients with hepatosplenic schistosomiasis mansoni and advanced periportal fibrosis.

• Main Authors: Luiz Arthur Calheiros Leite (Author), Adenor Almeida Pimenta Filho (Author), Caíque Silveira Martins da Fonseca (Author), Bianka Santana dos Santos (Author), Rita de Cássia dos Santos Ferreira (Author), Silvia Maria Lucena Montenegro (Author), Edmundo Pessoa Lopes (Author), Ana Lúcia Coutinho Domingues (Author), James Stuart Owen (Author), Vera Lúcia de Menezes Lima (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Schistosomiasis mansoni is an endemic parasitic disease and a public health problem in Northeast Brazil. In some patients, hepatic abnormalities lead to periportal fibrosis and result in the most severe clinical form, hepatosplenic schistosomiasis. This study aimed to evaluate whether ab...