Targeting bacterial growth in biofilm conditions: rational design of novel inhibitors to mitigate clinical and food contamination using QSAR

• Main Authors: Maria Galvez-Llompart (Author), Jesús Hierrezuelo (Author), Mariluz Blasco (Author), Riccardo Zanni (Author), Jorge Galvez (Author), Antonio de Vicente (Author), Alejandro Pérez-García (Author), Diego Romero (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Antimicrobial resistance (AMR) is a pressing global issue exacerbated by the abuse of antibiotics and the formation of bacterial biofilms, which cause up to 80% of human bacterial infections. This study presents a computational strategy to address AMR by developing three novel quantitative structure...