CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids

• Main Authors: Alexander Hennig (Author), Laura Wolf (Author), Beatrix Jahnke (Author), Heike Polster (Author), Therese Seidlitz (Author), Kristin Werner (Author), Daniela E. Aust (Author), Jochen Hampe (Author), Marius Distler (Author), Jürgen Weitz (Author), Daniel E. Stange (Author), Thilo Welsch (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Organoid cultures of human pancreatic ductal adenocarcinoma (PDAC) have become a promising tool for tumor subtyping and individualized chemosensitivity testing. PDACs have recently been grouped into different molecular subtypes with clinical impact based on cytokeratin-81 (KRT81) and hep...