Ketamine-induced neurotoxicity in neurodevelopment: A synopsis of main pathways based on recent in vivo experimental findings

• 主要な著者: Konstantina Kalopita (著者), Athanasios Armakolas (著者), Anastassios Philippou (著者), Apostolos Zarros (著者), Panagoula Angelogianni (著者)
• フォーマット: 図書
• 出版事項: Wolters Kluwer Medknow Publications, 2021-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Ketamine, a phencyclidine derivative and N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used as an anesthetic, analgesic, and sedative agent in daily pediatric practice. Experimental studies have suggested that early prenatal or postnatal exposure to ketamine can induce neuroapoptosis, a...