Rapid, actionable diagnosis of urban epidemic leptospirosis using a pathogenic Leptospira lipL32-based real-time PCR assay.

• Autores principales: Irina N Riediger (Autor), Robyn A Stoddard (Autor), Guilherme S Ribeiro (Autor), Sueli M Nakatani (Autor), Suzana D R Moreira (Autor), Irene Skraba (Autor), Alexander W Biondo (Autor), Mitermayer G Reis (Autor), Alex R Hoffmaster (Autor), Joseph M Vinetz (Autor), Albert I Ko (Autor), Elsio A Wunder (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2017-09-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

BACKGROUND:With a conservatively estimated 1 million cases of leptospirosis worldwide and a 5-10% fatality rate, the rapid diagnosis of leptospirosis leading to effective clinical and public health decision making is of high importance, and yet remains a challenge. METHODOLOGY:Based on parallel, pop...