Rapid, actionable diagnosis of urban epidemic leptospirosis using a pathogenic Leptospira lipL32-based real-time PCR assay.

• Main Authors: Irina N Riediger (Author), Robyn A Stoddard (Author), Guilherme S Ribeiro (Author), Sueli M Nakatani (Author), Suzana D R Moreira (Author), Irene Skraba (Author), Alexander W Biondo (Author), Mitermayer G Reis (Author), Alex R Hoffmaster (Author), Joseph M Vinetz (Author), Albert I Ko (Author), Elsio A Wunder (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:With a conservatively estimated 1 million cases of leptospirosis worldwide and a 5-10% fatality rate, the rapid diagnosis of leptospirosis leading to effective clinical and public health decision making is of high importance, and yet remains a challenge. METHODOLOGY:Based on parallel, pop...