Dual-targeting for brain-specific drug delivery: synthesis and biological evaluation

• Main Authors: Qiming Yue (Author), Yao Peng (Author), Yi Zhao (Author), Runxin Lu (Author), Qiuyi Fu (Author), Yang Chen (Author), Yang Yang (Author), Li Hai (Author), Li Guo (Author), Yong Wu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ibuprofen is one of the most potent non-steroid anti-inflammatory drugs (NSAIDs) and plays an important role in the treatment of neurodegenerative diseases. However, its poor brain penetration and serious side effects at therapeutic doses, has hindered its further application. Thus, it is of great i...