Hyaluronic Acid-Glycine-Cholesterol Conjugate-Based Nanoemulsion as a Potent Vaccine Adjuvant for T Cell-Mediated Immunity

• Main Authors: Chih-An Lin (Author), Hui-Min Ho (Author), Parthiban Venkatesan (Author), Chiung-Yi Huang (Author), Yu-Jhen Cheng (Author), Yu-Hsing Lin (Author), Hua-Yang Lin (Author), Tzu-Yang Chen (Author), Ming-Hsi Huang (Author), Ping-Shan Lai (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinical cases of allergic reaction that are due to excipients containing polyethylene glycol (PEG), a hydrophilic molecule commonly used in drug/vaccine formulations, has attracted much attention in recent years. In order to develop PEG-free adjuvants, we investigated the feasibility of natural ing...