Hyperoside ameliorates cerebral ischaemic-reperfusion injury by opening the TRPV4 channel in vivo through the IP3-PKC signalling pathway

• Main Authors: Lei Shi (Author), Chenchen Jiang (Author), Hanghang Xu (Author), Jiangping Wu (Author), Jiajun Lu (Author), Yuxiang He (Author), Xiuyun Yin (Author), Zhuo Chen (Author), Di Cao (Author), Xuebin Shen (Author), Xuefeng Hou (Author), Jun Han (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractContext Hyperoside (Hyp), one of the active flavones from Rhododendron (Ericaceae), has beneficial effects against cerebrovascular disease. However, the effect of Hyp on vasodilatation has not been elucidated.Objective To explore the effect of Hyp on vasodilatation in the cerebral basilar ar...