Protective Effects of Kirenol against Lipopolysaccharide-Induced Acute Lung Injury through the Modulation of the Proinflammatory NFκB Pathway and the AMPK2-/Nrf2-Mediated HO-1/AOE Pathway

• Main Authors: Frank Cheau-Feng Lin (Author), Shiuan-Shinn Lee (Author), Yi-Ching Li (Author), Yung-Chuan Ho (Author), Wen-Ying Chen (Author), Chun-Jung Chen (Author), Min-Wei Lee (Author), Kun-Lin Yeh (Author), Stella Chin-Shaw Tsai (Author), Yu-Hsiang Kuan (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Acute lung injury (ALI) is an acute and life-threatening inflammatory disease of the lung parenchyma that is associated with high mortality worldwide. No therapeutic strategies have been developed for the mitigation of the proinflammatory response that characterizes ALI. Kirenol has anti-inflammator...