U1 Adaptor Oligonucleotides Targeting BCL2 and GRM1 Suppress Growth of Human Melanoma Xenografts In Vivo

• मुख्य लेखकों: Rafal Goraczniak (लेखक), Brian A Wall (लेखक), Mark A Behlke (लेखक), Kim A Lennox (लेखक), Eric S Ho (लेखक), Nikolas H Zaphiros (लेखक), Christopher Jakubowski (लेखक), Neil R Patel (लेखक), Steven Zhao (लेखक), Carlo Magaway (लेखक), Stacey A Subbie (लेखक), Lumeng Jenny Yu (लेखक), Stephanie LaCava (लेखक), Kenneth R Reuhl (लेखक), Suzie Chen (लेखक), Samuel I Gunderson (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2013-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

U1 Adaptor is a recently discovered oligonucleotide-based gene-silencing technology with a unique mechanism of action that targets nuclear pre-mRNA processing. U1 Adaptors have two distinct functional domains, both of which must be present on the same oligonucleotide to exert their gene-silencing fu...