Topical Isotretinoin (TMB-001) Treatment for 12 Weeks Did Not Result in Clinically Relevant Laboratory Abnormalities in Participants with Congenital Ichthyosis in the Phase 2b CONTROL Study

• Главные авторы: Kalyani Marathe (Автор), Joyce M. C. Teng (Автор), Scott Guenthner (Автор), Christopher G. Bunick (Автор), Steven Kempers (Автор), Kimmie Eads (Автор), Leslie Castelo-Soccio (Автор), Alan M. Mendelsohn (Автор), Jessica Raiz (Автор), Dédée F. Murrell (Автор)
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• Опубликовано: Adis, Springer Healthcare, 2023-05-01T00:00:00Z.
• Предметы: article
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Abstract Introduction Treatment with oral retinoids can be effective in patients with congenital ichthyosis (CI) but may be associated with clinically significant laboratory changes. In this Phase 2b CONTROL study analysis, we characterize the effects of TMB-001, a novel topical isotretinoin formula...