Topical Isotretinoin (TMB-001) Treatment for 12 Weeks Did Not Result in Clinically Relevant Laboratory Abnormalities in Participants with Congenital Ichthyosis in the Phase 2b CONTROL Study

• Main Authors: Kalyani Marathe (Author), Joyce M. C. Teng (Author), Scott Guenthner (Author), Christopher G. Bunick (Author), Steven Kempers (Author), Kimmie Eads (Author), Leslie Castelo-Soccio (Author), Alan M. Mendelsohn (Author), Jessica Raiz (Author), Dédée F. Murrell (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Treatment with oral retinoids can be effective in patients with congenital ichthyosis (CI) but may be associated with clinically significant laboratory changes. In this Phase 2b CONTROL study analysis, we characterize the effects of TMB-001, a novel topical isotretinoin formula...