Neuroprotective effects of erythropoietin against hypoxic injury via modulation of the mitogen-activated protein kinase pathway and apoptosis

• Main Authors: Ji Eun Jeong (Author), Jae Hyun Park (Author), Chun Soo Kim (Author), Sang Lak Lee (Author), Hai Lee Chung (Author), Woo Taek Kim (Author), Eun Joo Lee (Author)
• Format: Book
• Published: Korean Pediatric Society, 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeHypoxic-ischemic encephalopathy is a significant cause of neonatal morbidity and mortality. Erythropoietin (EPO) is emerging as a therapeutic candidate for neuroprotection. Therefore, this study was designed to determine the neuroprotective role of recombinant human EPO (rHuEPO) and the possi...