Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs

• Autores principales: Yoshinobu Nagasawa (Autor), Kaori Sakai (Autor), Rui Kurimoto (Autor), Satoshi Kawakami (Autor), Megumi Aimoto (Autor), Akira Takahara (Autor)
• Formato: Libro
• Publicado: Elsevier, 2020-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

We investigated effects of isoflurane and sevoflurane on sparfloxacin-induced QT-interval prolongation in guinea pigs under the monitoring of electrocardiogram and monophasic action potential (MAP), which was compared with those of halothane or non-inhaled anesthetics ketamine/xylazine. Intravenous...