Differential effects of ketoconazole, fluconazole, and itraconazole on the pharmacokinetics of pyrotinib in vitro and in vivo

It has been reported that drug-drug interactions (DDIs) can affect the pharmacokinetics and pharmacodynamics of various oral drugs. To better understand the effects of azole antifungal drugs (ketoconazole, fluconazole, and itraconazole) on pyrotinib's pharmacokinetics, DDIs between pyrotinib an...

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Main Authors: Li Wang (Author), Fan Wu (Author), Jia Xu (Author), Yu Wang (Author), Weidong Fei (Author), Hui Jiang (Author), Peiwu Geng (Author), Quan Zhou (Author), Shuanghu Wang (Author), Yongquan Zheng (Author), Huadong Deng (Author)
Format: Book
Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
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