Senescence-Associated Molecular and Epigenetic Alterations in Mesenchymal Stem Cell Cultures from Amniotic Fluid of Normal and Fetus-Affected Pregnancy

• मुख्य लेखकों: Jūratė Savickienė (लेखक), Sandra Baronaitė (लेखक), Aistė Zentelytė (लेखक), Gražina Treigytė (लेखक), Rūta Navakauskienė (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2016-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Human amniotic-fluid-derived mesenchymal stem cells (AF-MSCs) are interesting for their multilineage differentiation potential and wide range of therapeutic applications due to the ease of culture expansion. However, MSCs undergo replicative senescence. So far, the molecular mechanisms that underlie...