Calponin 2 harnesses metabolic reprogramming to determine kidney fibrosis

• Main Authors: Yuan Gui (Author), Yuanyuan Wang (Author), Zachary Palanza (Author), Jack L. Wang (Author), Priya Gupta (Author), Jianling Tao (Author), Yi Qiao (Author), Geneva Hargis (Author), Donald L. Kreutzer (Author), Sheldon I. Bastacky (Author), Yanbao Yu (Author), Yanlin Wang (Author), Silvia Liu (Author), Haiyan Fu (Author), Dong Zhou (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: In the fibrotic kidneys, the extent of a formed deleterious microenvironment is determined by cellular mechanical forces. This process requires metabolism for energy. However, how cellular mechanics and metabolism are connected remains unclear. Methods: A multi-disciplinary approach was e...