Expansion of CD8+ T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors.

Expansion of CD8+ T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors.

<h4>Introduction</h4>Lassa virus is a priority pathogen for vaccine research and development, however the duration of cellular immunity and protection in Lassa fever (LF) survivors remains unclear.<h4>Methods</h4>We investigated Lassa virus specific CD8+ T cell responses in 9...

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Main Authors: Stephanie M LaVergne (Author), Saori Sakabe (Author), Mambu Momoh (Author), Lansana Kanneh (Author), Nell Bond (Author), Robert F Garry (Author), Donald S Grant (Author), Juan Carlos de la Torre (Author), Michael B A Oldstone (Author), John S Schieffelin (Author), Brian M Sullivan (Author)
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Published: Public Library of Science (PLoS), 2022-11-01T00:00:00Z.
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