Expansion of CD8+ T cell population in Lassa virus survivors with low T cell precursor frequency reveals durable immune response in most survivors.

• Principais autores: Stephanie M LaVergne (Autor), Saori Sakabe (Autor), Mambu Momoh (Autor), Lansana Kanneh (Autor), Nell Bond (Autor), Robert F Garry (Autor), Donald S Grant (Autor), Juan Carlos de la Torre (Autor), Michael B A Oldstone (Autor), John S Schieffelin (Autor), Brian M Sullivan (Autor)
• Formato: Livro
• Publicado em: Public Library of Science (PLoS), 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

<h4>Introduction</h4>Lassa virus is a priority pathogen for vaccine research and development, however the duration of cellular immunity and protection in Lassa fever (LF) survivors remains unclear.<h4>Methods</h4>We investigated Lassa virus specific CD8+ T cell responses in 9...