Resistance to Single-agent Chemotherapy for Low-risk Gestational Trophoblastic Neoplasia

• Main Authors: Shahrzad Sheikhhasani (Author), Aghdas Abdolrazaghnejad (Author), Azam sadat Mousavi (Author), Setareh Akhavan (Author), Narges Zamani (Author), Elham Feizabad (Author)
• Format: Book
• Published: Babol University of Medical Sciences, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Methotrexate (MTX) and actinomycin D (ActD) have been used as first-line chemotherapy agents in the treatment of low-risk gestational trophoblastic neoplasia (GTN). Although low-risk GTN is considered a curable disease, its reported primary remission rates of 49 to 93% reflect the diffic...