Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions

• Hoofdauteurs: Sumit K. Chaturvedi (Auteur), Arun Parupudi (Auteur), Kristian Juul-Madsen (Auteur), Ai Nguyen (Auteur), Thomas Vorup-Jensen (Auteur), Sonia Dragulin-Otto (Auteur), Huaying Zhao (Auteur), Reza Esfandiary (Auteur), Peter Schuck (Auteur)
• Formaat: Boek
• Gepubliceerd in: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Monoclonal antibodies are a class of biotherapeutics used for an increasing variety of disorders, including cancer, autoimmune, neurodegenerative, and viral diseases. Besides their antigen specificity, therapeutic use also mandates control of their solution interactions and colloidal properties in o...