Dermal Injection of Recombinant Filaggrin-2 Ameliorates UVB-Induced Epidermal Barrier Dysfunction and Photoaging

• Main Authors: Lu Li (Author), Yuan Liu (Author), Ruxue Chang (Author), Tao Ye (Author), Ziyi Li (Author), Rufei Huang (Author), Zhaoyang Wang (Author), Jingxian Deng (Author), Huan Xia (Author), Yan Yang (Author), Yadong Huang (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The epidermal barrier is vital for protecting the skin from environmental stressors and ultraviolet (UV) radiation. Filaggrin-2 (FLG2), a critical protein in the stratum corneum, plays a significant role in maintaining skin barrier homeostasis. However, the precise role of FLG2 in mitigating the adv...