Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni.

• Main Authors: Paul McCusker (Author), Md Yeunus Mian (Author), Guanguan Li (Author), Michael D Olp (Author), V V N Phani Babu Tiruveedhula (Author), Farjana Rashid (Author), Lalit Kumar Golani (Author), Ranjit S Verma (Author), Brian C Smith (Author), James M Cook (Author), John D Chan (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Parasitic flatworm infections (e.g. tapeworms and fluke worms) are treated by a limited number of drugs. In most cases, control is reliant upon praziquantel (PZQ) monotherapy. However, PZQ is ineffective against sexually immature parasites, and there have also been several concerning reports on cest...