Targeting the Endoplasmic Reticulum Stress-Linked PERK/GRP78/CHOP Pathway with Magnesium Sulfate Attenuates Chronic-Restraint-Stress-Induced Depression-like Neuropathology in Rats

• Главные авторы: Hany H. Arab (Автор), Ali Khames (Автор), Shuruq E. Alsufyani (Автор), Azza A. K. El-Sheikh (Автор), Amany M. Gad (Автор)
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• Опубликовано: MDPI AG, 2023-02-01T00:00:00Z.
• Предметы: article
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Magnesium sulfate has demonstrated marked neuroprotection in eclampsia, hypoxia, stroke, and post-traumatic brain injury rodent models. However, its potential impact against chronic-restraint-stress (CRS)-induced depression-like neuropathology and associated alterations in endoplasmic reticulum (ER)...