Genistein alleviates H2O2-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis

• Hauptverfasser: Guihua Wu (Verfasst von), Siming Li (Verfasst von), Guangjin Qu (Verfasst von), Jiajia Hua (Verfasst von), Jing Zong (Verfasst von), Xiaofeng Li (Verfasst von), Fanghui Xu (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Context Genistein (Gen) has shown protective effects against ageing process. Objective To explore the role of Gen on the senescence of H2O2-induced human umbilical vein endothelial cells (HUVECs) and investigate the possible mechanism. Materials and methods HUVECs were treated with different concent...