Caudal-Rostral Progression of Alpha Motoneuron Degeneration in the SOD1^G93A Mouse Model of Amyotrophic Lateral Sclerosis

• Κύριοι συγγραφείς: Alastair J. Kirby (Συγγραφέας), Thomas Palmer (Συγγραφέας), Richard J. Mead (Συγγραφέας), Ronaldo M. Ichiyama (Συγγραφέας), Samit Chakrabarty (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2022-05-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Mice with transgenic expression of human SOD1^G93A are a widely used model of ALS, with a caudal-rostral progression of motor impairment. Previous studies have quantified the progression of motoneuron (MN) degeneration based on size, even though alpha (α-) and gamma (γ-) MNs ov...