Effect of the N501Y Mutation on Ligands Complexed with SARS-CoV-2 RBD: Insights on Potential Drug Candidates for COVID-19

• Main Authors: Camila Fonseca Amorim da Silva (Author), Samanta Omae Camalhonte (Author), Michell de Oliveira Almeida (Author), Sheila Cruz Araujo (Author), Miriam Sannomiya (Author), João Henrique Ghilardi Lago (Author), Kathia Maria Honorio (Author)
• Format: Book
• Published: MDPI AG, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bioactive compounds against SARS-CoV-2 targets could be potential treatments for COVID-19. Inhibitors of the receptor-binding domain (RBD) on the viral spike protein can block its binding to the human angiotensin-converting enzyme type II (ACE2) receptor. This study presents ligands based on natural...