Profilin 1 Induces Tumor Metastasis by Promoting Microvesicle Secretion Through the ROCK 1/p-MLC Pathway in Non-Small Cell Lung Cancer

• मुख्य लेखकों: Ya Wang (लेखक), Yichen Lu (लेखक), Rongjun Wan (लेखक), Yang Wang (लेखक), Chunfang Zhang (लेखक), Min Li (लेखक), Pengbo Deng (लेखक), Liming Cao (लेखक), Chengping Hu (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Profilin 1 (PFN1), an actin-binding protein, plays contrasting roles in the metastasis of several cancers; however, its role in non-small cell lung cancer (NSCLC) metastasis remains unclear. Here, PFN1 expression was upregulated in metastatic NSCLC tissues. PFN1 overexpression significantly promotes...