Elevated Admission Base Deficit Is Associated with a Complex Dynamic Network of Systemic Inflammation Which Drives Clinical Trajectories in Blunt Trauma Patients

• Main Authors: Othman Abdul-Malak (Author), Yoram Vodovotz (Author), Akram Zaaqoq (Author), Jesse Guardado (Author), Khalid Almahmoud (Author), Jinling Yin (Author), Brian Zuckerbraun (Author), Andrew B. Peitzman (Author), Jason Sperry (Author), Timothy R. Billiar (Author), Rami A. Namas (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We hypothesized that elevated base deficit (BD) ≥ 4 mEq/L upon admission could be associated with an altered inflammatory response, which in turn may impact differential clinical trajectories. Using clinical and biobank data from 472 blunt trauma survivors, 154 patients were identified after excludi...