A competitive binding-mass spectrometry strategy for high-throughput evaluation of potential critical quality attributes of therapeutic monoclonal antibodies

Therapeutic monoclonal antibodies (mAbs) have a propensity to host a large number of chemical and enzymatical modifications that need to be properly assessed for their potential impact on target binding. Traditional strategies of assessing the criticality of these attributes often involve a laboriou...

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Asıl Yazarlar: Zhengqi Zhang (Yazar), Yuetian Yan (Yazar), Shunhai Wang (Yazar), Ning Li (Yazar)
Materyal Türü: Kitap
Baskı/Yayın Bilgisi: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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