A caveolin-1 dependent glucose-6-phosphatase trafficking contributes to hepatic glucose production

• Main Authors: Amandine Gautier-Stein (Author), Julien Chilloux (Author), Maud Soty (Author), Bernard Thorens (Author), Christophe Place (Author), Carine Zitoun (Author), Adeline Duchampt (Author), Lorine Da Costa (Author), Fabienne Rajas (Author), Christophe Lamaze (Author), Gilles Mithieux (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Deregulation of hepatic glucose production is a key driver in the pathogenesis of diabetes, but its short-term regulation is incompletely deciphered. According to textbooks, glucose is produced in the endoplasmic reticulum by glucose-6-phosphatase (G6Pase) and then exported in the blood b...