Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogenesis, and adipokine secretion of human abdominal subcutaneous adipocytes

• Hoofdauteurs: Lucia Berti (Auteur), Martin Irmler (Auteur), Marty Zdichavsky (Auteur), Tobias Meile (Auteur), Anja Böhm (Auteur), Norbert Stefan (Auteur), Andreas Fritsche (Auteur), Johannes Beckers (Auteur), Alfred Königsrainer (Auteur), Hans-Ulrich Häring (Auteur), Martin Hrabě de Angelis (Auteur), Harald Staiger (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2015-07-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Serum concentrations of the hepatokine fibroblast growth factor (FGF) 21 are elevated in obesity, type-2 diabetes, and the metabolic syndrome. We asked whether FGF21 levels differ between subjects with metabolically healthy vs. unhealthy obesity (MHO vs. MUHO), opening the possibility tha...