The coagulopathy in sepsis: significance and implications for treatment

• Main Authors: Berardino Pollio (Author), Mauro Pagliarino (Author), Carlo Scolfaro (Author), Paola Saracco (Author), Fabio Timeus (Author), Pasquale Vitale (Author)
• Format: Book
• Published: MDPI AG, 2011-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sepsis related coagulopathy ranges from mild laboratory alterations up to severe disseminated intravascular coagulation (DIC). There is evidence that DIC is involved in the pathogenesis of microvascular dysfunction contributing to organ failure. Additionally, the systemic activation of coagulation,...