Analysis of the safety and efficacy of different plasma concentrations of pirfenidone in patients with idiopathic pulmonary fibrosis

• Main Authors: Hui Li (Author), Jing Yang (Author), Shanshan Chen (Author), Peile Wang (Author), Xueqing Yu (Author), Qingwei Zhou (Author), Xiaojian Zhang (Author), Guojun Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The high incidence and mortality of idiopathic pulmonary fibrosis (IPF) have led to the widespread use of antifibrotic drugs such as pirfenidone; however, the associated adverse reactions greatly vary among individuals and the dose is not fixed. To date, no reliable blood concentration range of pirf...