Plasmodium falciparum rhoptry neck protein 4 has conserved regions mediating interactions with receptors on human erythrocytes and hepatocyte membrane

• Main Authors: Fredy A. Pulido-Quevedo (Author), Gabriela Arévalo-Pinzón (Author), Jeimmy J. Castañeda-Ramírez (Author), Adriana Barreto-Santamaría (Author), Manuel E. Patarroyo (Author), Manuel A. Patarroyo (Author)
• Format: Book
• Published: Elsevier, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Plasmodium falciparum-related malaria represents a serious worldwide public health problem due to its high mortality rates. P. falciparum expresses rhoptry neck protein 4 (PfRON4) in merozoite and sporozoite rhoptries, it participates in tight junction-TJ formation via the AMA-1/RON complex and is r...