Evaluation of [⁶⁸Ga]Ga-DOTA-AeK as a Potential Imaging Tool for PET Imaging of Cell Wall Synthesis in Bacterial Infections

• Main Authors: Palesa C. Koatale (Author), Mick M. Welling (Author), Sipho Mdanda (Author), Amanda Mdlophane (Author), John Takyi-Williams (Author), Chrisna Durandt (Author), Iman van den Bout (Author), Frederik Cleeren (Author), Mike M. Sathekge (Author), Thomas Ebenhan (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ability of bacteria to recycle exogenous amino acid-based peptides and amino sugars for peptidoglycan biosynthesis was extensively investigated using optical imaging. In particular, fluorescent AeK-NBD was effectively utilized to study the peptidoglycan recycling pathway in Gram-negative bacteri...