Type 2 Inflammation Contributes to Skin Barrier Dysfunction in Atopic Dermatitis

• Main Authors: Lisa A. Beck (Author), Michael J. Cork (Author), Masayuki Amagai (Author), Anna De Benedetto (Author), Kenji Kabashima (Author), Jennifer D. Hamilton (Author), Ana B. Rossi (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Skin barrier dysfunction, a defining feature of atopic dermatitis (AD), arises from multiple interacting systems. In AD, skin inflammation is caused by host-environment interactions involving keratinocytes as well as tissue-resident immune cells such as type 2 innate lymphoid cells, basophils, mast...