Multifunctional polymeric micelle-based chemo-immunotherapy with immune checkpoint blockade for efficient treatment of orthotopic and metastatic breast cancer

• প্রধান লেখক: Jiaojie Wei (লেখক), Yang Long (লেখক), Rong Guo (লেখক), Xinlei Liu (লেখক), Xian Tang (লেখক), Jingdong Rao (লেখক), Sheng Yin (লেখক), Zhirong Zhang (লেখক), Man Li (লেখক), Qin He (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Elsevier, 2019-07-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Immunotherapy has become a highly promising paradigm for cancer treatment. Herein, a chemo-immunotherapy was developed by encapsulating chemotherapeutic drug doxorubicin (DOX) and Toll-like receptor 7 agonist imiquimod (IMQ) in low molecular weight heparin (LMWH)-d-α-tocopheryl succinate (TOS) micel...