Pharmacological Profile of KUL-7211, a Selective -Adrenoceptor Agonist, in Isolated Ureteral Smooth Muscle

• Main Authors: Yoshitaka Tomiyama (Author), Makoto Murakami (Author), Kohichi Hayakawa (Author), Katsuyoshi Akiyama (Author), Yoshinobu Yamazaki (Author), Masami Kojima (Author), Nobuo Shibata (Author), Masuo Akahane (Author)
• Format: Book
• Published: Elsevier, 2003-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since, in the human ureter, both β2- and β3-adrenoceptors mediate adrenergic-stimulation-induced relaxation, selective β2-/β3-adrenoceptor agonists might prove clinically useful for relieving ureteral colic and promoting stone passage. We evaluated the β-adrenoceptor subtype selectivity and ureteral...