The Effect of 1,2,4-Triazole-3-thiol Derivatives Bearing Hydrazone Moiety on Cancer Cell Migration and Growth of Melanoma, Breast, and Pancreatic Cancer Spheroids

• Main Authors: Aida Šermukšnytė (Author), Kristina Kantminienė (Author), Ilona Jonuškienė (Author), Ingrida Tumosienė (Author), Vilma Petrikaitė (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

4-Phenyl-3-[2-(phenylamino)ethyl]-1<i>H</i>-1,2,4-triazole-5(4<i>H</i>)-thione was used as a starting compound for the synthesis of the corresponding 1,2,4-triazol-3-ylthioacetohydrazide, which reacts with isatins and various aldehydes bearing aromatic and heterocyclic moieti...