A Rodent Model of Human-Dose-Equivalent 5-Fluorouracil: Toxicity in the Liver, Kidneys, and Lungs

• Main Authors: Mariana Conceição da Silva (Author), Lilian Catarim Fabiano (Author), Karile Cristina da Costa Salomão (Author), Pedro Luiz Zonta de Freitas (Author), Camila Quaglio Neves (Author), Stephanie Carvalho Borges (Author), Maria das Graças de Souza Carvalho (Author), Ana Cristina Breithaupt-Faloppa (Author), André Alexandre de Thomaz (Author), Aline Mara dos Santos (Author), Nilza Cristina Buttow (Author)
• Format: Book
• Published: MDPI AG, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

5-Fluorouracil (5-FU) is a chemotherapy drug widely used to treat a range of cancer types, despite the recurrence of adverse reactions. Therefore, information on its side effects when administered at a clinically recommended dose is relevant. On this basis, we examined the effects of the 5-FU clinic...