Multi-omics analysis of gut-brain axis reveals novel microbial and neurotransmitter signatures in patients with arteriosclerotic cerebral small vessel disease

• Main Authors: Jiayuan Huang (Author), Sanxin Liu (Author), Peijie Li (Author), Lei Wei (Author), Gan Lin (Author), Jiahao Lin (Author), Yuting Luo (Author), Yixin Liu (Author), Yudan Mao (Author), Hengfang Ruan (Author), Bing Qin (Author), Ping Fan (Author), Tingting Lu (Author), Wei Cai (Author), Haotong Yi (Author), Xiangyu Mou (Author), Zhengqi Lu (Author), Wenjing Zhao (Author), Aimin Wu (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Arteriosclerotic cerebral small vessel disease (aCSVD) is a major cause of stroke and dementia. Although its underlying pathogenesis remains poorly understood, both inflammaging and gut microbiota dysbiosis have been hypothesized to play significant roles. This study investigated the role of gut mic...