Survival and Intra-Nuclear Trafficking of Burkholderia pseudomallei: Strategies of Evasion from Immune Surveillance?

• Main Authors: Jamuna Vadivelu (Author), Kumutha Malar Vellasamy (Author), Jaikumar Thimma (Author), Vanitha Mariappan (Author), Wen-Tyng Kang (Author), Leang-Chung Choh (Author), Esaki M Shankar (Author), Kum Thong Wong (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:During infection, successful bacterial clearance is achieved via the host immune system acting in conjunction with appropriate antibiotic therapy. However, it still remains a tip of the iceberg as to where persistent pathogens namely, Burkholderia pseudomallei (B. pseudomallei) reside/hid...